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NKp30 Polyclonal Antibody
NKp30 Polyclonal Antibody
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NKp30 Polyclonal Antibody
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经销商客户: ¥214.5
实验室客户: ¥292.5
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商品描述

商品属性

Target:NKp30

Fields:Natural killer cell mediated cytotoxicity

Gene Name:NCR3

Protein Name:Natural cytotoxicity triggering receptor 3

Human Gene Id:259197

Human Swiss Prot No:O14931

Rat Swiss Prot No:Q8CFD9

Immunogen:The antiserum was produced against synthesized peptide derived from human NCR3. AA range:104-153

Specificity:NKp30 Polyclonal Antibody detects endogenous levels of NKp30 protein.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source:Polyclonal, Rabbit,IgG

Dilution:WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration:1 mg/ml

Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name:NCR3;1C7;LY117;Natural cytotoxicity triggering receptor 3;Activating natural killer receptor p30;Natural killer cell p30-related protein;NK-p30;NKp30;CD antigen CD337

Observed Band(KD):22kD

Background: The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010],

Function:function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,polymorphism:A genetic variation in NCR3 is associated with mild malaria suceptibility [MIM:609148].,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,subunit:Interacts with CD3Z.,tissue specificity:Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.,

Subcellular Location:Cell membrane ; Single-pass type I membrane protein .

Expression:Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.

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