Target：NGDN

Gene Name：NGDN C14orf120

Protein Name：Neuroguidin (EIF4E-binding protein)

Human Gene Id：25983

Human Swiss Prot No：Q8NEJ9

Mouse Swiss Prot No：Q9DB96

Immunogen：Synthesized peptide derived from human protein . at AA range: 240-320

Specificity：NGDN Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：34kD

Background： Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008],

Function：function:Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs.,similarity:Belongs to the SAS10 family.,subcellular location:Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites.,subunit:Interacts with CPEB1 and EIF4E.,

Subcellular Location：Nucleus . Nucleus, nucleolus . Chromosome, centromere . Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell projection, filopodium . Detected in axons, dendrites and filopodia. Colocalized with EIF4E in neurites (By similarity). Translocated from nucleolus to nuclear foci in response to UV damage. .

Expression： Brain,Epithelium,Placenta,