Target：ADP-GK

Fields：Glycolysis / Gluconeogenesis;Metabolic pathways;Carbon metabolism

Gene Name：ADPGK

Protein Name：ADP-dependent glucokinase

Human Gene Id：83440

Human Swiss Prot No：Q9BRR6

Mouse Gene Id：72141

Mouse Swiss Prot No：Q8VDL4

Immunogen：The antiserum was produced against synthesized peptide derived from human ADPGK. AA range:241-290

Specificity：ADP-GK Polyclonal Antibody detects endogenous levels of ADP-GK protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ADPGK;PSEC0260;ADP-dependent glucokinase;ADP-GK;ADPGK;RbBP-35

Observed Band(KD)：47kD

Background： ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008],

Function：catalytic activity:ADP + D-glucose = AMP + D-glucose 6-phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency.,pathway:Carbohydrate degradation; glycolysis.,similarity:Belongs to the ADP-dependent glucokinase family.,similarity:Contains 1 ADPK (ADP-dependent kinase) domain.,subunit:Monomer.,

Subcellular Location：Secreted .

Expression： Brain,Heart,Kidney,Lymph node,Teratocarcinoma,Testis,