Target：NF-YC
Fields：Antigen processing and presentation;Tuberculosis
Gene Name：NFYC
Protein Name：Nuclear transcription factor Y subunit gamma
Human Gene Id：4802
Human Swiss Prot No：Q13952
Mouse Gene Id：18046
Mouse Swiss Prot No：P70353
Rat Gene Id：25337
Rat Swiss Prot No：Q62725
Immunogen：The antiserum was produced against synthesized peptide derived from human NFYC. AA range:1-50
Specificity：NF-YC Polyclonal Antibody detects endogenous levels of NF-YC protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：NFYC;Nuclear transcription factor Y subunit gamma;CAAT box DNA-binding protein subunit C;Nuclear transcription factor Y subunit C;NF-YC;Transactivator HSM-1/2
Observed Band(KD)：50kD
Background： This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
Function：function:Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.,similarity:Belongs to the NFYC/HAP5 subunit family.,subunit:Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding.,
Subcellular Location：Nucleus.
Expression： Brain,Lymph node,Synovial membrane tissue,
