Target：Neuropilin-2

Gene Name：NRP2

Protein Name：Neuropilin-2

Human Gene Id：8828

Human Swiss Prot No：O60462

Mouse Gene Id：18187

Mouse Swiss Prot No：O35375

Rat Gene Id：81527

Rat Swiss Prot No：O35276

Immunogen：The antiserum was produced against synthesized peptide derived from the Internal region of human NRP2. AA range:791-840

Specificity：Neuropilin-2 Polyclonal Antibody detects endogenous levels of Neuropilin-2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NRP2;VEGF165R2;Neuropilin-2;Vascular endothelial cell growth factor 165 receptor 2

Observed Band(KD)：100kD

Background： This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Function：function:High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.,similarity:Belongs to the neuropilin family.,similarity:Contains 1 MAM domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 F5/8 type C domains.,subunit:Heterodimer with NRP1 (Probable). Binds PLXNB1.,

Subcellular Location：Membrane ; Single-pass type I membrane protein .; [Isoform s9]: Secreted .

Expression： Brain,Human endometrium carcinoma cell line,Liver,Mammary gland,Ovary,Prostate adenocarcino