Target：Neuronal PAS1

Gene Name：NPAS1

Protein Name：Neuronal PAS domain-containing protein 1

Human Gene Id：4861

Human Swiss Prot No：Q99742

Mouse Swiss Prot No：P97459

Immunogen：The antiserum was produced against synthesized peptide derived from human NPAS1. AA range:445-494

Specificity：Neuronal PAS1 Polyclonal Antibody detects endogenous levels of Neuronal PAS1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NPAS1;BHLHE11;MOP5;PASD5;Neuronal PAS domain-containing protein 1;Neuronal PAS1;Basic-helix-loop-helix-PAS protein MOP5;Class E basic helix-loop-helix protein 11;bHLHe11;Member of PAS protein 5;PAS domain-containing protein 5

Observed Band(KD)：62kD

Background： The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008],

Function：function:May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Interacts with ARNT.,

Subcellular Location：Nucleus .

Expression： Brain,Fetal brain,Hepatoma,