Target：Neuron Navigator 2

Gene Name：NAV2

Protein Name：Neuron navigator 2

Human Gene Id：89797

Human Swiss Prot No：Q8IVL1

Immunogen：Synthesized peptide derived from Neuron Navigator 2 . at AA range: 2040-2120

Specificity：Neuron Navigator 2 Polyclonal Antibody detects endogenous levels of Neuron Navigator 2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NAV2;HELAD1;KIAA1419;POMFIL2;RAINB1;STEERIN2;Neuron navigator 2;Helicase APC down-regulated 1;Pore membrane and/or filament-interacting-like protein 2;Retinoic acid inducible in neuroblastoma 1;Steerin-2;Unc-53 homolog 2;unc53H2

Molecular Weight(Da)：268kD

Background： This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Function：alternative products:Additional isoforms may exist,caution:PubMed:15158073 experiments have been carried out in mouse.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,developmental stage:Highly expressed in the nervous system of developing embryos. Also expressed in fetal heart, liver and kidney.,function:Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.,induction:By all-trans retinoic acid (atRA). Up-regulated in colorectal carcinomas.,similarity:Belongs to the Nav/unc-53 family.,similarity:Contains 1 CH (calponin-homology) domain.,tissue specificity:Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expr

Subcellular Location：Nucleus .

Expression：Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.