Target:NDUFC2
Fields:Oxidative phosphorylation;Metabolic pathways;Thermogenesis;Retrograde endocannabinoid signaling;Non-alcoholic fatty liver disease;Alzheimer disease;Parkinson disease;Amyotrophic lateral sclerosis;Huntington disease;Prion disease;Pathways of neurodegeneration - multiple diseases;Chemical carcinogenesis - reactive oxygen species;Diabetic cardiomyopathy
Gene Name:NDUFC2
Protein Name:NADH dehydrogenase [ubiquinone] 1 subunit C2
Human Gene Id:4718
Human Swiss Prot No:O95298
Mouse Swiss Prot No:Q9CQ54
Immunogen:The antiserum was produced against synthesized peptide derived from human NDUC2. AA range:51-100
Specificity:NDUFC2 Polyclonal Antibody detects endogenous levels of NDUFC2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NDUFC2;HLC1;NADH dehydrogenase [ubiquinone] 1 subunit C2;Complex I-B14.5b;CI-B14.5b;Human lung cancer oncogene 1 protein;HLC-1;NADH-ubiquinone oxidoreductase subunit B14.5b
Molecular Weight(Da):14kD
Background:function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFC2 subunit family.,subunit:Complex I is composed of 45 different subunits.,
Function:function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFC2 subunit family.,subunit:Complex I is composed of 45 different subunits.,
Subcellular Location:Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
Expression: Kidney,Ovary,Umbilical cord blood,