Target:NDUFC1
Fields:Oxidative phosphorylation;Metabolic pathways;Thermogenesis;Retrograde endocannabinoid signaling;Non-alcoholic fatty liver disease;Alzheimer disease;Parkinson disease;Amyotrophic lateral sclerosis;Huntington disease;Prion disease;Pathways of neurodegeneration - multiple diseases;Chemical carcinogenesis - reactive oxygen species;Diabetic cardiomyopathy
Gene Name:NDUFC1
Protein Name:NADH dehydrogenase [ubiquinone] 1 subunit C1 mitochondrial
Human Gene Id:4717
Human Swiss Prot No:O43677
Mouse Gene Id:66377
Mouse Swiss Prot No:Q9CQY9
Immunogen:Synthesized peptide derived from NDUFC1 . at AA range: 40-120
Specificity:NDUFC1 Polyclonal Antibody detects endogenous levels of NDUFC1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NDUFC1;NADH dehydrogenase [ubiquinone] 1 subunit C1; mitochondrial;Complex I-KFYI;CI-KFYI;NADH-ubiquinone oxidoreductase KFYI subunit
Molecular Weight(Da):9kD
Background: The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
Function:function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFC1 subunit family.,subunit:Complex I is composed of 45 different subunits.,
Subcellular Location:Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
Expression: Brain,Heart,Skin,Umbilical cord blood,