Target:NAC2
Fields:Calcium signaling pathway;cGMP-PKG signaling pathway;Cardiac muscle contraction;Adrenergic signaling in cardiomyocytes;Apelin signaling pathway;Olfactory transduction;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Mineral absorption;Hypertrophic cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy;Dilated cardiomyopathy
Gene Name:SLC8A2 KIAA1087 NCX2
Protein Name:Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2)
Human Gene Id:6543
Human Swiss Prot No:Q9UPR5
Rat Swiss Prot No:P48768
Immunogen:Synthesized peptide derived from human protein . at AA range: 380-460
Specificity:NAC2 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):101kD
Background:enzyme regulation:By ATP.,function:Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily.,similarity:Contains 2 Calx-beta domains.,
Function:enzyme regulation:By ATP.,function:Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores.,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC8 subfamily.,similarity:Contains 2 Calx-beta domains.,
Subcellular Location:Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane ; Multi-pass membrane protein . Perikaryon . Cell projection, dendrite . Cell projection, dendritic spine .
Expression: Amygdala,Brain,