Target:MRP-L50
Gene Name:MRPL50
Protein Name:39S ribosomal protein L50 mitochondrial
Human Gene Id:54534
Human Swiss Prot No:Q8N5N7
Mouse Swiss Prot No:Q8VDT9
Immunogen:The antiserum was produced against synthesized peptide derived from human MRPL50. AA range:109-158
Specificity:MRP-L50 Polyclonal Antibody detects endogenous levels of MRP-L50 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MRPL50;39S ribosomal protein L50; mitochondrial;L50mt;MRP-L50
Observed Band(KD):22kD
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008],
Subcellular Location:Mitochondrion .
Expression: Carcinoma,Epithelium,Hepatoma,Skin,