Target:MRP-L49
Gene Name:MRPL49
Protein Name:39S ribosomal protein L49 mitochondrial
Human Gene Id:740
Human Swiss Prot No:Q13405
Mouse Swiss Prot No:Q9CQ40
Immunogen:Synthesized peptide derived from MRP-L49 . at AA range: 10-90
Specificity:MRP-L49 Polyclonal Antibody detects endogenous levels of MRP-L49 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MRPL49;C11orf4;NOF1;OK/SW-cl.67;39S ribosomal protein L49; mitochondrial;L49mt;MRP-L49;Neighbor of FAU;NOF;Protein NOF1
Observed Band(KD):19kD
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011],
Function:similarity:Belongs to the ribosomal protein L49em family.,tissue specificity:Ubiquitous.,
Subcellular Location:Mitochondrion .
Expression:Ubiquitous.