Target：MKL2

Gene Name：MKL2 KIAA1243 MRTFB

Protein Name：MKL/myocardin-like protein 2 (Megakaryoblastic leukemia 2) (Myocardin-related transcription factor B) (MRTF-B)

Human Gene Id：57496

Human Swiss Prot No：Q9ULH7

Mouse Swiss Prot No：P59759

Immunogen：Synthesized peptide derived from human protein . at AA range: 500-580

Specificity：MKL2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：119kD

Background：domain:The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity.,function:Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.,PTM:O-glycosylated.,similarity:Contains 1 SAP domain.,similarity:Contains 3 RPEL repeats.,subunit:Interacts with MKL1 and SRF.,

Function：domain:The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity.,function:Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.,PTM:O-glycosylated.,similarity:Contains 1 SAP domain.,similarity:Contains 3 RPEL repeats.,subunit:Interacts with MKL1 and SRF.,

Subcellular Location：Nucleus .

Expression： Amygdala,Brain,Cervix carcinoma,Epithelium,Medulla oblongata,Normal pituitary,Pancr