Target：Rhophilin

Gene Name：RHPN1

Protein Name：Rhophilin-1

Human Gene Id：114822

Human Swiss Prot No：Q8TCX5

Mouse Swiss Prot No：Q61085

Immunogen：The antiserum was produced against synthesized peptide derived from human RHPN1. AA range:474-523

Specificity：Rhophilin Polyclonal Antibody detects endogenous levels of Rhophilin protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RHPN1;KIAA1929;Rhophilin-1;GTP-Rho-binding protein 1

Observed Band(KD)：100kD

Background：domain:The PDZ domain mediates interaction with ROPN1.,function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Binds specifically to GTP-Rho. Interacts with ROPN1.,

Function：domain:The PDZ domain mediates interaction with ROPN1.,function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Binds specifically to GTP-Rho. Interacts with ROPN1.,

Subcellular Location：cytosol,

Expression： Blood,Brain,