Target：RHOJ

Fields：Salmonella infection

Gene Name：RHOJ ARHJ RASL7B RHOI TCL

Protein Name：Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)

Human Gene Id：57381

Human Swiss Prot No：Q9H4E5

Mouse Swiss Prot No：Q9ER71

Immunogen：Synthesized peptide derived from human protein . at AA range: 30-110

Specificity：RHOJ Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：23kD

Background： This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011],

Function：function:GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Interacts with the CRIB domains of proteins such as Pak1 and Was/Wasp.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side . Localization to the plasma membrane is regulated by GLUL. .

Expression：Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.