Target：p44S10
Fields：Proteasome;Alzheimer disease;Parkinson disease;Amyotrophic lateral sclerosis;Huntington disease;Spinocerebellar ataxia;Prion disease;Pathways of neurodegeneration - multiple diseases;Epstein-Barr virus infection
Gene Name：PSMD6
Protein Name：26S proteasome non-ATPase regulatory subunit 6
Human Gene Id：9861
Human Swiss Prot No：Q15008
Mouse Gene Id：66413
Mouse Swiss Prot No：Q99JI4
Immunogen：The antiserum was produced against synthesized peptide derived from human PSMD6. AA range:201-250
Specificity：p44S10 Polyclonal Antibody detects endogenous levels of p44S10 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：PSMD6;KIAA0107;PFAAP4;26S proteasome non-ATPase regulatory subunit 6;26S proteasome regulatory subunit RPN7;26S proteasome regulatory subunit S10;Breast cancer-associated protein SGA-113M;Phosphonoformate immuno-associated protein 4;
Observed Band(KD)：45kD
Background： This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012],
Function：function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Belongs to the proteasome subunit S10 family.,similarity:Contains 1 PCI domain.,subunit:Component of the PA700 complex.,
Subcellular Location：proteasome complex,nucleoplasm,cytosol,proteasome regulatory particle,proteasome accessory complex,extracellular exosome,
Expression： Bone marrow,Lymph,Mammary cancer,Ovary,Placenta,Testis,
