Target：P2RY8

Fields：Neuroactive ligand-receptor interaction

Gene Name：P2RY8

Protein Name：P2Y purinoceptor 8

Human Gene Id：286530

Human Swiss Prot No：Q86VZ1

Immunogen：The antiserum was produced against synthesized peptide derived from human P2RY8. AA range:192-241

Specificity：P2RY8 Polyclonal Antibody detects endogenous levels of P2RY8 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：P2RY8;P2Y purinoceptor 8;P2Y8

Observed Band(KD)：41kD

Background：purinergic receptor P2Y8(P2RY8) Homo sapiens The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008],

Function：function:Probable receptor for purines coupled to G-proteins.,induction:Down-regulated during granulocytic regulation.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.