Target:Pax-1
Gene Name:PAX1
Protein Name:Paired box protein Pax-1
Human Gene Id:5075
Human Swiss Prot No:P15863
Mouse Swiss Prot No:P09084
Immunogen:The antiserum was produced against synthesized peptide derived from human Pax-1. AA range:318-367
Specificity:Pax-1 Polyclonal Antibody detects endogenous levels of Pax-1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:PAX1;HUP48;Paired box protein Pax-1;HuP48
Observed Band(KD):36kD
Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012],
Function:function:This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column.,similarity:Contains 1 paired domain.,
Subcellular Location:Nucleus.