Target:PGRP4
Gene Name:PGLYRP4 PGRPIB SBBI67
Protein Name:Peptidoglycan recognition protein 4 (Peptidoglycan recognition protein I-beta) (PGLYRPIbeta) (PGRP-I-beta) (Peptidoglycan recognition protein intermediate beta)
Human Gene Id:57115
Human Swiss Prot No:Q96LB8
Mouse Swiss Prot No:Q0VB07
Immunogen:Synthesized peptide derived from part region of human protein AA range: 81-130
Specificity:PGRP4 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):41kD
Background: Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014],
Function:function:Binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May play a role in innate immunity.,similarity:Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.,tissue specificity:High expression in the esophagus. Expressed also to a much lesser extent in the tonsils and thymus.,
Subcellular Location:Secreted .
Expression:Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.