Target：PSK2

Fields：MAPK signaling pathway

Gene Name：TAOK1

Protein Name：Serine/threonine-protein kinase TAO1

Human Gene Id：57551

Human Swiss Prot No：Q7L7X3

Mouse Gene Id：216965

Mouse Swiss Prot No：Q5F2E8

Rat Gene Id：286993

Rat Swiss Prot No：O88664

Immunogen：The antiserum was produced against synthesized peptide derived from human TAOK1. AA range:431-480

Specificity：PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TAOK1;KIAA1361;MAP3K16;MARKK;Serine/threonine-protein kinase TAO1;Kinase from chicken homolog B;hKFC-B;MARK Kinase;MARKK;Prostate-derived sterile 20-like kinase 2;PSK-2;PSK2;Prostate-derived STE20-like kinase 2;Thousand and one

Observed Band(KD)：120kD

Background：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,

Subcellular Location：Cytoplasm .

Expression：Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.