Target：PRDX5

Fields：Peroxisome

Gene Name：PRDX5 ACR1 SBBI10

Protein Name：Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (

Human Gene Id：25824

Human Swiss Prot No：P30044

Mouse Swiss Prot No：P99029

Rat Swiss Prot No：Q9R063

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：PRDX5 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：23kD

Background： This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Function：catalytic activity:2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.,function:Reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided through the thioredoxin system. Involved in intracellular redox signaling.,similarity:Belongs to the peroxiredoxin 2 family.,similarity:Contains 1 thioredoxin domain.,subunit:Monomer.,tissue specificity:Widely expressed.,

Subcellular Location：[Isoform Mitochondrial]: Mitochondrion .; [Isoform Cytoplasmic+peroxisomal]: Cytoplasm . Peroxisome matrix . Imported into peroxisomes via peroxisomal targeting signal 1 receptor PEX5. .

Expression：Widely expressed.