Target:Rab 24
Gene Name:RAB24
Protein Name:Ras-related protein Rab-24
Human Gene Id:53917
Human Swiss Prot No:Q969Q5
Mouse Gene Id:19336
Mouse Swiss Prot No:P35290
Immunogen:Synthesized peptide derived from Rab 24 . at AA range: 90-170
Specificity:Rab 24 Polyclonal Antibody detects endogenous levels of Rab 24 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RAB24;Ras-related protein Rab-24
Molecular Weight(Da):23kD
Background: RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009],
Function:function:May be involved in autophagy-related processes.,induction:By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into post-mitotic neurons (NTN2) (at protein level).,miscellaneous:The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase activity. As a result, the predominant nucleotide associated with the protein is GTP.,PTM:Isoprenylation is inefficient compared to other Rab family members.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Only about 20-25% is recovered in the particulate fraction.,subunit:Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB.,
Subcellular Location:Cytoplasm, cytosol . Membrane ; Lipid-anchor . Only about 20-25% is recovered in the particulate fraction. .
Expression: Amygdala,Pancreas,Skin,Uterus,Whole embryo,