Target：Rab 18

Gene Name：RAB18

Protein Name：Ras-related protein Rab-18

Human Gene Id：22931

Human Swiss Prot No：Q9NP72

Mouse Gene Id：19330

Mouse Swiss Prot No：P35293

Rat Gene Id：307039

Rat Swiss Prot No：Q5EB77

Immunogen：The antiserum was produced against synthesized peptide derived from human RAB18. AA range:103-152

Specificity：Rab 18 Polyclonal Antibody detects endogenous levels of Rab 18 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RAB18;Ras-related protein Rab-18

Observed Band(KD)：28kD

Background： The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

Function：function:Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous.,

Subcellular Location：Apical cell membrane . Lipid droplet .

Expression：Ubiquitous.