Target：Rab 11B

Fields：Endocytosis;AMPK signaling pathway;Vasopressin-regulated water reabsorption;Influenza A

Gene Name：RAB11B

Protein Name：Ras-related protein Rab-11B

Human Gene Id：9230

Human Swiss Prot No：Q15907

Mouse Gene Id：19326

Mouse Swiss Prot No：P46638

Rat Gene Id：79434

Rat Swiss Prot No：O35509

Immunogen：The antiserum was produced against synthesized peptide derived from human RAB11B. AA range:164-213

Specificity：Rab 11B Polyclonal Antibody detects endogenous levels of Rab 11B protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RAB11B;YPT3;Ras-related protein Rab-11B;GTP-binding protein YPT3

Observed Band(KD)：28kD

Background： The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010],

Function：function:Possesses GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4.,

Subcellular Location：Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus. .

Expression： B-cell lymphoma,Brain,Cerebellum,Muscle,