Target：RAB5B

Fields：Ras signaling pathway;Endocytosis;Phagosome;Vasopressin-regulated water reabsorption;Salmonella infection;Amoebiasis;Tuberculosis

Gene Name：RAB5B

Protein Name：Ras-related protein Rab-5B

Human Gene Id：5869

Human Swiss Prot No：P61020

Mouse Swiss Prot No：P61021

Immunogen：Synthesized peptide derived from human protein . at AA range: 90-170

Specificity：RAB5B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：23kD

Background：enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN2 and RIN3, which probably regulate its pathway, possibly by acting as GEFs.,

Function：enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP.,function:Protein transport. Probably involved in vesicular traffic.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Enriched in stage I melanosomes.,subunit:Binds EEA1. Interacts with RIN2 and RIN3, which probably regulate its pathway, possibly by acting as GEFs.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Enriched in stage I melanosomes. .

Expression： Brain,Endometrium,Eye,PNS,Skin,