Target：RGPA1

Fields：Ras signaling pathway

Gene Name：RALGAPA1 GARNL1 KIAA0884 TULIP1

Protein Name：Ral GTPase-activating protein subunit alpha-1 (GAP-related-interacting partner to E12) (GRIPE) (GTPase-activating Rap/Ran-GAP domain-like 1) (Tuberin-like protein 1) (p240)

Human Gene Id：253959

Human Swiss Prot No：Q6GYQ0

Mouse Swiss Prot No：Q6GYP7

Rat Swiss Prot No：O55007

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RGPA1 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：223kD

Background： This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016],

Function：regulation of small GTPase mediated signal transduction,

Subcellular Location：Cytoplasm . Nucleus . Translocated to the nucleus, when associated with TCF3/E12. .

Expression：Widely expressed.