Target：RASM

Fields：MAPK signaling pathway;Ras signaling pathway;Rap1 signaling pathway;Phospholipase D signaling pathway;Mitophagy - animal;Autophagy - animal;Cellular senescence;Apelin signaling pathway;C-type lectin receptor signaling pathway;Regulation of actin cytoskeleton;Proteoglycans in cancer

Gene Name：MRAS RRAS3

Protein Name：Ras-related protein M-Ras (Ras-related protein R-Ras3)

Human Gene Id：22808

Human Swiss Prot No：O14807

Mouse Swiss Prot No：O08989

Rat Swiss Prot No：P97538

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RASM Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：22kD

Background： This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Function：function:May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.,induction:By interleukin-9, but not by IL-2 or IL-4.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with RGL3.,tissue specificity:Expression highly restricted to the brain and heart.,

Subcellular Location：Cell membrane ; Lipid-anchor ; Cytoplasmic side .

Expression：Expression highly restricted to the brain and heart.