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RAB32 Polyclonal Antibody
RAB32 Polyclonal Antibody
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RAB32 Polyclonal Antibody
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经销商客户: ¥440.0
实验室客户: ¥600.0
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Target:RAB32

Gene Name:RAB32

Protein Name:Ras-related protein Rab-32

Human Gene Id:10981

Human Swiss Prot No:Q13637

Mouse Swiss Prot No:Q9CZE3

Immunogen:Synthesized peptide derived from human protein . at AA range: 160-240

Specificity:RAB32 Polyclonal Antibody detects endogenous levels of protein.

Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source:Polyclonal, Rabbit,IgG

Dilution:WB 1:500-2000 ELISA 1:5000-20000

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration:1 mg/ml

Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD):24kD

Background: The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this gene may be linked to leprosy. [provided by RefSeq, Dec 2015],

Function:function:Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.,

Subcellular Location:Mitochondrion . Mitochondrion outer membrane ; Lipid-anchor . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). .

Expression:Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.

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