Target：RASF3

Gene Name：RASSF3

Protein Name：Ras association domain-containing protein 3

Human Gene Id：283349

Human Swiss Prot No：Q86WH2

Mouse Swiss Prot No：Q99P51

Immunogen：Synthesized peptide derived from human protein . at AA range: 160-240

Specificity：RASF3 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：26kD

Background： The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003],

Function：caution:Has been termed RASSF5 by Ref.1.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subcellular location:Localized to microtubules in vascular endothelial cells.,tissue specificity:Widely expressed.,

Subcellular Location：Cytoplasm . Cytoplasm, cytoskeleton . Localized to microtubules in vascular endothelial cells.

Expression：Widely expressed.