Target：RASEF

Gene Name：RASEF RAB45

Protein Name：Ras and EF-hand domain-containing protein (Ras-related protein Rab-45)

Human Gene Id：158158

Human Swiss Prot No：Q8IZ41

Mouse Swiss Prot No：Q5RI75

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：RASEF Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：81kD

Background： This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012],

Function：function:Binds predominantly GDP, and also GTP.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Down-regulated in cutaneous melanoma cells but not in breast cancer cells.,

Subcellular Location：Cytoplasm, perinuclear region .

Expression：Down-regulated in cutaneous melanoma cells but not in breast cancer cells.