Target：TBX6

Gene Name：TBX6

Protein Name：T-box transcription factor TBX6 (T-box protein 6)

Human Gene Id：6911

Human Swiss Prot No：O95947

Mouse Swiss Prot No：P70327

Rat Swiss Prot No：D3ZJK7

Immunogen：Synthesized peptide derived from human protein . at AA range: 230-310

Specificity：TBX6 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：47kD

Background： This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008],

Function：developmental stage:Expressed during gastrulation and during a second phase in some adult tissues.,function:Probable transcriptional regulator involved in developmental processes. Could be required for specification of paraxial mesoderm structures during gastrulation.,similarity:Contains 1 T-box DNA-binding domain.,subunit:Forms a dimeric complex with DNA (in vitro).,tissue specificity:Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.,

Subcellular Location：Nucleus .

Expression：Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.