欢迎来到启研生物[ 会员登录 ] [ 立即注册 ]
400-812-0026

购物车0

您购物车为空,赶紧选购吧!
TBX3 Polyclonal Antibody
TBX3 Polyclonal Antibody
<
>
TBX3 Polyclonal Antibody
市场价格
经销商客户: ¥440.0
实验室客户: ¥600.0
近期销售量10 用户评价:comment rank 5()
文件与质量管理
浏览历史 [清空]

商品描述

商品属性

Target:TBX3

Fields:Signaling pathways regulating pluripotency of stem cells

Gene Name:TBX3

Protein Name:T-box transcription factor TBX3

Human Gene Id:6926

Human Swiss Prot No:O15119

Mouse Gene Id:21386

Mouse Swiss Prot No:P70324

Rat Gene Id:353305

Rat Swiss Prot No:Q7TST9

Immunogen:The antiserum was produced against synthesized peptide derived from human TBX3. AA range:301-350

Specificity:TBX3 Polyclonal Antibody detects endogenous levels of TBX3 protein.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source:Polyclonal, Rabbit,IgG

Dilution:WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration:1 mg/ml

Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name:TBX3;T-box transcription factor TBX3;T-box protein 3

Observed Band(KD):79kD

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008],

Function:disease:Defects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.,function:Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Widely expressed.,

Subcellular Location:Nucleus .

Expression:Widely expressed.

广告说明