Target：TBX22

Gene Name：TBX22

Protein Name：T-box transcription factor TBX22

Human Gene Id：50945

Human Swiss Prot No：Q9Y458

Mouse Swiss Prot No：Q8K402

Immunogen：The antiserum was produced against synthesized peptide derived from human TBX22. AA range:1-50

Specificity：TBX22 Polyclonal Antibody detects endogenous levels of TBX22 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TBX22;TBOX22;T-box transcription factor TBX22;T-box protein 22

Observed Band(KD)：58kD

Background：T-box 22(TBX22) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Function：disease:Defects in TBX22 are the cause of X-linked cleft palate with ankyloglossia (CPX) [MIM:303400].,function:Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Seems to be expressed at a low level.,

Subcellular Location：Nucleus .

Expression：Seems to be expressed at a low level.