Target:TFIIH p62
Fields:Basal transcription factors;Nucleotide excision repair;Viral carcinogenesis
Gene Name:GTF2H1
Protein Name:General transcription factor IIH subunit 1
Human Gene Id:2965
Human Swiss Prot No:P32780
Mouse Gene Id:14884
Mouse Swiss Prot No:Q9DBA9
Immunogen:The antiserum was produced against synthesized peptide derived from human TF2H1. AA range:15-64
Specificity:TFIIH p62 Polyclonal Antibody detects endogenous levels of TFIIH p62 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:GTF2H1;BTF2;General transcription factor IIH subunit 1;Basic transcription factor 2 62 kDa subunit;BTF2 p62;General transcription factor IIH polypeptide 1;TFIIH basal transcription factor complex p62 subunit
Observed Band(KD):57kD
Background:function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,PTM:Phosphorylated.,similarity:Contains 2 BSD domains.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with PUF60.,
Function:function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,PTM:Phosphorylated.,similarity:Contains 2 BSD domains.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with PUF60.,
Subcellular Location:Nucleus.
Expression: Liver,Lung,