Target：TFIIE-β

Fields：Basal transcription factors;Viral carcinogenesis

Gene Name：GTF2E2

Protein Name：Transcription initiation factor IIE subunit beta

Human Gene Id：2961

Human Swiss Prot No：P29084

Mouse Gene Id：68153

Mouse Swiss Prot No：Q9D902

Immunogen：The antiserum was produced against synthesized peptide derived from human TF2E2. AA range:151-200

Specificity：TFIIE-β Polyclonal Antibody detects endogenous levels of TFIIE-β protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GTF2E2;TF2E2;Transcription initiation factor IIE subunit beta;TFIIE-beta;General transcription factor IIE subunit 2

Observed Band(KD)：33kD

Background：function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.,similarity:Belongs to the TFIIE beta subunit family.,similarity:Contains 1 TFIIE beta DNA-binding domain.,subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H.,

Function：function:Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.,similarity:Belongs to the TFIIE beta subunit family.,similarity:Contains 1 TFIIE beta DNA-binding domain.,subunit:Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H.,

Subcellular Location：Nucleus .

Expression： Skin,