Target:TNF18
Fields:Cytokine-cytokine receptor interaction
Gene Name:TNFSF18 AITRL GITRL TL6 UNQ149/PRO175
Protein Name:Tumor necrosis factor ligand superfamily member 18 (Activation-inducible TNF-related ligand) (AITRL) (Glucocorticoid-induced TNF-related ligand) (hGITRL)
Human Gene Id:8995
Human Swiss Prot No:Q9UNG2
Mouse Swiss Prot No:Q7TS55
Immunogen:Synthesized peptide derived from part region of human protein AA range: 101-150
Specificity:TNF18 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):21kD
Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008],
Function:function:Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.,induction:Up-regulated after stimulation by lipopolysaccharides.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer .,tissue specificity:Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.,
Subcellular Location:Cell membrane ; Single-pass type II membrane protein .
Expression:Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.