Target：TP53INP2

Fields：Autophagy - animal

Gene Name：TP53INP2

Protein Name：Tumor protein p53-inducible nuclear protein 2

Human Gene Id：58476

Human Swiss Prot No：Q8IXH6

Mouse Gene Id：68728

Mouse Swiss Prot No：Q8CFU8

Immunogen：The antiserum was produced against synthesized peptide derived from the C-terminal region of human TP53INP2. AA range:161-210

Specificity：TP53INP2 Polyclonal Antibody detects endogenous levels of TP53INP2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：TP53INP2;C20orf110;DOR;PINH;Tumor protein p53-inducible nuclear protein 2;Diabetes and obesity-regulated gene;p53-inducible protein U;PIG-U

Observed Band(KD)：24kD

Background：tumor protein p53 inducible nuclear protein 2(TP53INP2) Homo sapiens The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes. [provided by RefSeq, Jul 2016],

Subcellular Location：Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.

Expression： Eye,Heart,