Target:WDR44
Gene Name:WDR44
Protein Name:WD repeat-containing protein 44 (Rabphilin-11)
Human Gene Id:54521
Human Swiss Prot No:Q5JSH3
Mouse Swiss Prot No:Q6NVE8
Rat Swiss Prot No:Q9R037
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:WDR44 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):100kD
Background: This gene encodes a protein that interacts with the small GTPase rab11. A similar protein in rat binds the GTP-containing active form of rab11. This protein may play a role in endosome recycling. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
Function:function:Downstream effector for RAB11. May be involved in vesicle recycling.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 WD repeats.,subcellular location:Colocalized with RAB11 along microtubules oriented toward lamellipodia.,subunit:Interacts with the GTP-bound form of RAB11 when membrane-associated. Does not bind to other Rab and Rho small G proteins.,
Subcellular Location:Cytoplasm, cytosol. Cytoplasm, perinuclear region. Endosome membrane. Golgi apparatus, trans-Golgi network. Colocalized with RAB11 along microtubules oriented toward lamellipodia. .
Expression: Amygdala,Colon endothelium,Endometrial tumor,Epithelium,Teratocarcinoma,Testis,Tong