Target:WDHD1
Gene Name:WDHD1
Protein Name:WD repeat and HMG-box DNA-binding protein 1
Human Gene Id:11169
Human Swiss Prot No:O75717
Mouse Swiss Prot No:P59328
Immunogen:The antiserum was produced against synthesized peptide derived from human WDHD1. AA range:721-770
Specificity:WDHD1 Polyclonal Antibody detects endogenous levels of WDHD1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:WDHD1;AND1;WD repeat and HMG-box DNA-binding protein 1;Acidic nucleoplasmic DNA-binding protein 1;And-1
Observed Band(KD):126kD
Background: The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Function:caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Binds DNA with high affinity. May also be involved in protein-protein interactions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HMG box DNA-binding domain.,similarity:Contains 7 WD repeats.,
Subcellular Location:Nucleus, nucleoplasm .
Expression: Embryonal rhabdomyosarcoma,Epithelium,Fetal brain,Liver,Ski