Target：ZIP7

Fields：Alzheimer disease;Parkinson disease

Gene Name：SLC39A7

Protein Name：Zinc transporter SLC39A7

Human Gene Id：7922

Human Swiss Prot No：Q92504

Mouse Gene Id：14977

Mouse Swiss Prot No：Q31125

Immunogen：The antiserum was produced against synthesized peptide derived from human SLC39A7. AA range:131-180

Specificity：ZIP7 Polyclonal Antibody detects endogenous levels of ZIP7 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SLC39A7;HKE4;RING5;Zinc transporter SLC39A7;Histidine-rich membrane protein Ke4;Really interesting new gene 5 protein;Solute carrier family 39 member 7

Observed Band(KD)：50kD

Background： The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Function：similarity:Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.,tissue specificity:Major expression in placenta, lung, kidney and pancreas.,

Subcellular Location：Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus, cis-Golgi network membrane ; Multi-pass membrane protein .

Expression：Widely expressed.