Target：ZNF420

Fields：Herpes simplex virus 1 infection

Gene Name：ZNF420

Protein Name：Zinc finger protein 420

Human Gene Id：147923

Human Swiss Prot No：Q8TAQ5

Immunogen：The antiserum was produced against synthesized peptide derived from human ZNF420. AA range:301-350

Specificity：ZNF420 Polyclonal Antibody detects endogenous levels of ZNF420 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ZNF420;Zinc finger protein 420

Observed Band(KD)：80kD

Background：zinc finger protein 420(ZNF420) Homo sapiens The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016],

Function：function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 KRAB domain.,similarity:Contains 19 C2H2-type zinc fingers.,

Subcellular Location：Nucleus .

Expression： Muscle,Placenta,Testis,