Target：Relaxin Receptor 3

Fields：Neuroactive ligand-receptor interaction;Relaxin signaling pathway

Gene Name：RXFP3

Protein Name：Relaxin-3 receptor 1

Human Gene Id：51289

Human Swiss Prot No：Q9NSD7

Mouse Gene Id：239336

Mouse Swiss Prot No：Q8BGE9

Immunogen：The antiserum was produced against synthesized peptide derived from human RXFP3. AA range:161-210

Specificity：Relaxin Receptor 3 Polyclonal Antibody detects endogenous levels of Relaxin Receptor 3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RXFP3;RLN3R1;SALPR;Relaxin-3 receptor 1;RLN3 receptor 1;G protein-coupled receptor SALPR;G-protein coupled receptor GPCR135;Relaxin family peptide receptor 3;Somatostatin- and angiotensin-like peptide receptor

Observed Band(KD)：51kD

Background：function:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,

Function：function:Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.,

Subcellular Location：Cell membrane; Multi-pass membrane protein.

Expression：Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.