Target：IGS11

Fields：Cell adhesion molecules

Gene Name：IGSF11 BTIGSF CXADRL1 VSIG3

Protein Name：Immunoglobulin superfamily member 11 (IgSF11) (Brain and testis-specific immunoglobulin superfamily protein) (Bt-IGSF) (V-set and immunoglobulin domain-containing protein 3)

Human Gene Id：152404

Human Swiss Prot No：Q5DX21

Mouse Swiss Prot No：P0C673

Rat Swiss Prot No：Q5U2P2

Immunogen：Synthesized peptide derived from human protein . at AA range: 110-190

Specificity：IGS11 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：47kD

Background： IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005],

Function：function:Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.,miscellaneous:The last 20 cytoplasmic amino-acids are not required for the cell adhesion function.,PTM:N-glycosylated.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.,

Subcellular Location：Cell membrane ; Single-pass type I membrane protein .

Expression：Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.