Target：IFITM3

Gene Name：IFITM3

Protein Name：Interferon-induced transmembrane protein 3

Human Gene Id：10410

Human Swiss Prot No：Q01628

Mouse Swiss Prot No：Q9CQW9

Immunogen：The antiserum was produced against synthesized peptide derived from human IFM3. AA range:1-50

Specificity：IFITM3 Polyclonal Antibody detects endogenous levels of IFITM3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：IFITM3;Interferon-induced transmembrane protein 3;Dispanin subfamily A member 2b;DSPA2b;Interferon-inducible protein 1-8U

Observed Band(KD)：15kD

Background： The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012],

Function：induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,

Subcellular Location：Cell membrane ; Single-pass type II membrane protein . Late endosome membrane ; Single-pass type II membrane protein . Early endosome membrane ; Single-pass type II membrane protein. Lysosome membrane ; Single-pass type II membrane protein . Cytoplasm, perinuclear region . Co-localizes with BRI3 isoform 1 at the perinuclear region. .

Expression： Brain,Cervix,Vascular endothelial cell,