Target：Syndecan-2

Fields：Cell adhesion molecules;Malaria;Proteoglycans in cancer;Fluid shear stress and atherosclerosis

Gene Name：SDC2

Protein Name：Syndecan-2

Human Gene Id：6383

Human Swiss Prot No：P34741

Mouse Swiss Prot No：P43407

Immunogen：The antiserum was produced against synthesized peptide derived from human SDC2. AA range:81-130

Specificity：Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SDC2;HSPG1;Syndecan-2;SYND2;Fibroglycan;Heparan sulfate proteoglycan core protein;HSPG;CD antigen CD362

Observed Band(KD)：22kD

Background： The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008],

Function：function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,

Subcellular Location：Membrane; Single-pass type I membrane protein.

Expression： Brain,Embryo,Lung fibroblast,Muscle,Testis,