Target:AQP8
Fields:Bile secretion
Gene Name:AQP8
Protein Name:Aquaporin-8 (AQP-8)
Human Gene Id:343
Human Swiss Prot No:O94778
Mouse Swiss Prot No:P56404
Rat Swiss Prot No:P56405
Immunogen:Synthesized peptide derived from human protein . at AA range: 70-150
Specificity:AQP8 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):28kD
Background: Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008],
Function:domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed only in pancreas and colon.,
Subcellular Location:Mitochondrion membrane ; Multi-pass membrane protein .
Expression:Detected in the sperm midpiece (at protein level) (PubMed:28042826). Expressed only in pancreas and colon.