Target:AQP6
Gene Name:AQP6 AQP2L
Protein Name:Aquaporin-6 (AQP-6) (Aquaporin-2-like) (Kidney-specific aquaporin) (hKID)
Human Gene Id:363
Human Swiss Prot No:Q13520
Mouse Swiss Prot No:Q8C4A0
Rat Swiss Prot No:Q9WTY0
Immunogen:Synthesized peptide derived from human protein . at AA range: 60-140
Specificity:AQP6 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):31kD
Background: The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008],
Function:domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,
Subcellular Location:Cytoplasmic vesicle membrane ; Multi-pass membrane protein .
Expression: Kidney,Testis,