Target：Tubulin α

Fields：Phagosome;Apoptosis;Tight junction;Gap junction;Alzheimer disease;Parkinson disease;Amyotrophic lateral sclerosis;Huntington disease;Prion disease;Pathways of neurodegeneration - multiple diseases;Pathogenic Escherichia coli infection;Salmonella infection

Gene Name：TUBA1B

Protein Name：Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain)

Human Gene Id：7277

Human Swiss Prot No：P68363

Mouse Swiss Prot No：P05213

Rat Swiss Prot No：Q6P9V9

Immunogen：Synthetic Peptide of α-tubulin (Acetyl Lys40)

Specificity：α-tubulin (Acetyl Lys40) protein detects endogenous levels of α-tubulin (Acetyl Lys40)

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Monoclonal, Mouse

Dilution：WB 1:1000-2000, IHC 1:100-200, IF 1:50-200

Purification：The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：Tubulin alpha-1B chain (Alpha-tubulin ubiquitous;Tubulin K-alpha-1;Tubulin alpha-ubiquitous chain)

Observed Band(KD)：52kD

Background：function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,

Function：function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,

Subcellular Location：Cytoplasm, cytoskeleton.

Expression： Brain,Cajal-Retzius cell,Colon,Embryonic kidney,Eye,Fetal brain cortex,Keratinocyte