Target:p70 S6 kinase α
Fields:EGFR tyrosine kinase inhibitor resistance;Endocrine resistance;ErbB signaling pathway;HIF-1 signaling pathway;Autophagy - animal;mTOR signaling pathway;PI3K-Akt signaling pathway;AMPK signaling pathway;Longevity regulating pathway;Longevity regulating pathway - multiple species;TGF-beta signaling pathway;Apelin signaling pathway;Fc gamma R-mediated phagocytosis;Thermogenesis;Insulin signaling pathway;Insulin resistance;Shigellosis;Human cytomegalovirus infection;Human papillomavirus infection;Human immunodeficiency virus 1 infection;Pathways in cancer;Proteoglycans in cancer;Chemical carcinogenesis - receptor activation;Colorectal cancer;Pancreatic cancer;Acute myeloid leukemia;Breast cancer;Hepatocellular carcinoma;Gastric cancer;Choline metabolism in cancer;PD-L1 expression and PD-1 checkpoint pathway in cancer
Gene Name:RPS6KB1 STK14A P70S6K
Protein Name:Ribosomal protein S6 kinase beta-1
Human Gene Id:6198
Human Swiss Prot No:P23443
Mouse Gene Id:72508
Mouse Swiss Prot No:Q8BSK8
Rat Gene Id:83840
Rat Swiss Prot No:P67999
Immunogen:The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Ser434. AA range:401-450
Specificity:Phospho-p70 S6 kinase α (S434) Polyclonal Antibody detects endogenous levels of p70 S6 kinase α protein only when phosphorylated at S434.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RPS6KB1;STK14A;Ribosomal protein S6 kinase beta-1;S6K-beta-1;S6K1;70 kDa ribosomal protein S6 kinase 1;P70S6K1;p70-S6K 1;Ribosomal protein S6 kinase I;Serine/threonine-protein kinase 14A;p70 ribosomal S6 kinase alpha;p70 S6 kinas
Observed Band(KD):60