Target：Ras-GRF1

Gene Name：RASGRF1

Protein Name：Ras-specific guanine nucleotide-releasing factor 1

Human Swiss Prot No：Q13972

Mouse Gene Id：19417

Rat Gene Id：192213

Rat Swiss Prot No：P28818

Immunogen：The antiserum was produced against synthesized peptide derived from mouse Ras-GRF1 around the phosphorylation site of Ser916. AA range:882-931

Specificity：Phospho-Ras-GRF1 (S916) Polyclonal Antibody detects endogenous levels of Ras-GRF1 protein only when phosphorylated at S916.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RASGRF1;CDC25;GNRP;GRF1;Ras-specific guanine nucleotide-releasing factor 1;Ras-GRF1;Guanine nucleotide-releasing protein;GNRP;Ras-specific nucleotide exchange factor CDC25

Molecular Weight(Da)：145kD

Background：]RASGRF1 (Ras Protein Specific Guanine Nucleotide Releasing Factor 1) is a Protein Coding gene. Diseases associated with RASGRF1 include bleeding disorder, platelet-type, 18 and refractive error. Among its related pathways are Signaling by GPCR and Immune System. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RALGDS. romotes the exchange of Ras-bound GDP by GTP.